How to solve the problem of particle agglomeration in the dryer
May 12, 2020
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Four reasons, including sealing problems, oxidation in contact with air, excessive temperature of the dryer, instability of the granules, etc., and corresponding solutions are given.
Equipment tightness
If a small amount of water vapor enters the dryer, it is easy for the water vapor and the surface of the particles to stick to each other, and agglomeration occurs.
In view of this situation, what the user should do is to ensure the tightness of the dryer and prevent water vapor from entering the dryer. The industry said that users need to know the tightness of the equipment when choosing a dryer.
"The brand is one aspect. The choice is also the key when choosing. The key is to look at the workmanship. The key is the flatness of the grind. You can turn around and feel the friction, but this requires experience. In addition, the lid cannot be used during operation. The buckle is finished, you have to rotate it and push it around. "The industry said.
Oxidation problem
If the particles are exposed to oxygen in the air, they will slowly oxidize, causing the surface material properties to change, thereby forming agglomerates.
It is reported that some granules, such as traditional Chinese medicine granules, tend to absorb water and segregate during storage, which affects quality. In addition, the granules after moisture absorption are more susceptible to oxidation, hydrolysis, and mildew, and have appearance changes and reduced active ingredients. The industry recommends that for such situations, you can start with early production and choose excipients with less hygroscopicity or change the proportion of excipients. In addition, for Chinese medicine granules, you can strictly control the moisture in the production process and use excipients with low hygroscopicity as much as possible. Optimize granulation methods.
Dryer temperature is too high
If the temperature of the dryer is too high, it will melt it. Industry insiders pointed out that granules are not crystals, have no fixed melting point, and are easy to melt under high temperature, and agglomeration occurs, just like white sugar or brown sugar. Zh
In this regard, the industry recommends that if the environment is affected, the dryer can be placed in a cool and dry place, avoiding places where the temperature is too high or the humidity is too heavy. Zh
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