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Introduction

Solid phase extraction is a sample preparation method by which a compound dissolved or suspended in a liquid mixture is separated from other compounds in the mixture according to its physical and chemical properties.The analytical laboratory uses solid phase extraction to concentrate and purify the sample for analysis.Solid phase extraction can be used to separate target analytes from a variety of matrices,including urine,blood,water,beverages,soil and animal tissue.

Advantages

1.Simplification and composite purification of composite sample matrix

2.Reduce ion suppression or enhancement in MS applications

3.Ability to fractionate sample matrices to analyze compounds by class

4.Trace concentrations of very low concentrations of compounds

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